Results
| PMID | 11119747 |
| Gene Name | IL11 |
| Condition | Endometriosis (Pelvic) |
| Association |
Associated |
| Population size | 60 |
| Population details | 60 women undergoing laparoscopic surgery for benign gynecological indications |
| Sex | Female |
| Associated genes | IL-11 |
| Other associated phenotypes |
Pelvic endometriosis |
|
Fertil Steril. 2000 Dec;74(6):1182-6. Gazvani, M R| Bates, M| Vince, G| Christmas, S| Lewis-Jones, D I| Kingsland, C Reproductive Medicine Unit, Liverpool Women's Hospital, Liverpool, United Kingdom. m.r.gazvani@abdn.ac.uk OBJECTIVE: To determine the peritoneal fluid concentrations of interleukin-11 (IL-11) in women with endometriosis as compared with the control group. DESIGN: A prospective, controlled study. SETTING: The obstetrics and gynecology department of a teaching hospital and a university immunology department. PATIENT(S): Sixty consecutive women undergoing laparoscopic surgery for benign gynecological indications. INTERVENTION(S): Peritoneal fluid was obtained during laparoscopy, and the concentration of IL-11 was measured. MAIN OUTCOME MEASURE(S): Concentration of IL-11 in correlation with the presence of endometriosis, its stage, and the phase of the menstrual cycle. RESULT(S): IL-11 was detectable in the peritoneal fluid of 64% of women tested. Concentrations of IL-11 showed no correlation with the presence of endometriosis, the American Fertility Society stage of the disease, or the phase of the menstrual cycle. CONCLUSION(S): We found no evidence to suggest that IL-11 is involved in the pathogenesis of pelvic endometriosis. Mesh Terms: Adult| Ascitic Fluid/*metabolism| Endometriosis/*metabolism/pathology/physiopathology| Female| Humans| Interleukin-11/*metabolism| Menstrual Cycle| Osmolar Concentration| Prospective Studies| Reference Values|DA 2001/02/28 10:01 |
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